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Centrum has been related to the side effect of Obtundation. If you are taking Centrum and have experienced Obtundation this information may be of use to you.  
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Centrum Drug Insert (if available)
IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.
Centrum Ingredients
  • Beta carotene
  • Calcium phosphate
  • Acide folique
  • Cianocobalamina
  • Cholecalciferol
  • Cupric oxide
  • Cyanocobalamin
  • 530
  • Biotin
  • Biotina
  • Aneurine
  • Biotine
  • Biotinum
  • Carotene
  • Acido folico
  • Acidum folicum
  • Calcium carbonate
  • Copper (cupric oxide)
  • Cycobeminum
  • D-pantothenic acid
  • E101
  • Cyanocobalamine
  • E306
  • Folate
  • Folic acid
  • Cyanocobalaminum
  • Retinol
  • Retinol acetate
  • Tocopherol
  • Vitamin B6
  • Retinolum
  • Tricalcium phosphate
  • Vitamin B9
  • Riboflavin
  • Iron (ferrous fumarate)
  • Niacinamide
  • Magnesium oxide
  • Lactoflavin
  • Nicotinamide
  • Iodine
  • Magnesii oxidum
  • Vitaminum a
  • Vitamin B2
  • Riboflavin e101
  • Vitamin B 12 gelatine coated (0,1 %)
  • Tiamina
  • Riboflavinum
  • Thiamin
  • Thiamine
  • Vitamin B3
  • Vitamin B1
  • Riboflavina
  • Vitamin C
  • Vitamin A
  • Provitamin A
  • Vitamin D
  • Vitamin B12
  • Pyridoxine
  • Vitamin D3
  • Riboflavine
  • Vitamin A acetate
  • Vitamin E
  • Vitamin H
  • Thiaminum
  • Vitamine a
  • Riboflavine e101
    • Centrum - Obtundation Outcomes
  • Not yet recovered - 1 Reported Cases
    • Centrum - Obtundation Involvements
  • Concomitant - 1 Reported Cases
    • Other Reactions Reported While Taking Centrum
    nausea - 21 Reports efficacy, lack of - 20 Reports vomiting - 16 Reports pruritus - 10 Reports
    headache - 9 Reports dizziness - 9 Reports fever - 8 Reports rash - 8 Reports
    fatigue - 8 Reports diarrhoea - 8 Reports pain - 8 Reports weight decrease - 7 Reports
    abdominal pain - 7 Reports anxiety - 7 Reports itching - 6 Reports rash erythematous - 6 Reports
    breath shortness - 6 Reports hyperglycaemia - 6 Reports dehydration - 5 Reports urticaria - 5 Reports
    neutropenia - 5 Reports hives - 5 Reports fall - 5 Reports back pain - 5 Reports
    malaise - 4 Reports tremor - 4 Reports chills - 4 Reports pneumonia - 4 Reports
    confusion - 4 Reports leucopenia - 4 Reports haemoglobin decreased - 4 Reports throat tightness - 4 Reports
    coughing - 4 Reports sgot increased - 4 Reports sgpt increased - 4 Reports depression - 4 Reports
    palpitation - 4 Reports joint pain - 4 Reports condition aggravated - 4 Reports constipation - 3 Reports
    asthenia - 3 Reports mouth dry - 3 Reports sweating increased - 3 Reports vision abnormal - 3 Reports
    dyspnoea - 3 Reports myocardial infarction - 3 Reports appetite lost - 3 Reports hepatic failure - 3 Reports
    paranoid reaction - 3 Reports pain neck/shoulder - 3 Reports walking difficulty - 3 Reports arthralgia - 3 Reports
    rash maculo-papular - 3 Reports drowsiness - 3 Reports weakness generalized - 3 Reports throat sore - 3 Reports
    medication error - 3 Reports coronary artery disorder - 3 Reports hypoglycaemia - 3 Reports stomach upset - 3 Reports
    muscle pain - 3 Reports haematemesis - 2 Reports anorexia - 2 Reports ataxia - 2 Reports
    myalgia - 2 Reports face oedema - 2 Reports bradycardia - 2 Reports hypotension - 2 Reports
    suicidal tendency - 2 Reports somnolence - 2 Reports weight increase - 2 Reports light-headed feeling - 2 Reports
    congestive heart failure - 2 Reports pancreatitis - 2 Reports nosebleed - 2 Reports cerebral haemorrhage - 2 Reports
    cardiac arrest - 2 Reports erythema - 2 Reports alkaline phosphatase serum incr - 2 Reports jaundice - 2 Reports
    aggressiveness - 2 Reports dysarthria - 2 Reports respiratory distress - 2 Reports coma - 2 Reports
    temperature elevation - 2 Reports creatinine blood increased - 2 Reports hot flushes - 2 Reports muscle ache - 2 Reports
    unconsciousness - 2 Reports muscle disorder - 2 Reports muscle cramp - 2 Reports tachycardia - 2 Reports
    lethargy - 2 Reports syncope - 2 Reports consciousness decreased - 2 Reports thrombocytopenia - 2 Reports
    creatine kinase increased - 2 Reports skin discolouration - 2 Reports feeling unwell - 2 Reports hepatitis - 2 Reports
    intestinal obstruction - 2 Reports hepatic enzymes increased - 2 Reports bloating - 2 Reports throat swelling non-specific - 2 Reports
    rigors - 2 Reports paraesthesia - 2 Reports insomnia - 2 Reports flushing - 2 Reports
    breathing difficult - 2 Reports irritability - 2 Reports pulse rate increased - 2 Reports arthritis rheumatoid aggravated - 2 Reports
    burning mucosal - 2 Reports erythrocytopenia - 2 Reports drug level increased - 2 Reports anaemia - 2 Reports
    fluid retention in tissues - 2 Reports memory loss - 2 Reports blood in stool - 2 Reports injection site reaction - 2 Reports
    neoplasm nos - 2 Reports arthropathy - 2 Reports fracture pathological - 2 Reports dysequilibrium - 2 Reports
    fibrillation atrial - 2 Reports leukocytosis - 2 Reports dyspepsia - 1 Reports carcinoma - 1 Reports
    speech disorder - 1 Reports eye abnormality - 1 Reports pharyngitis - 1 Reports pallor - 1 Reports
    depression aggravated - 1 Reports swallowing difficult - 1 Reports thinking abnormal - 1 Reports therapeutic effect unexpected - 1 Reports
    sugar blood level increased - 1 Reports cpk increased - 1 Reports chest discomfort - 1 Reports bleeding time increased - 1 Reports
    pancreatitis haemorrhagic - 1 Reports lymphoma-like disorder - 1 Reports salivary gland infection - 1 Reports diabetes mellitus - 1 Reports
    oedema of extremities - 1 Reports fat disorder - 1 Reports angioedema - 1 Reports glottic oedema - 1 Reports
    tongue swelling non-specific - 1 Reports basal cell carcinoma - 1 Reports blood pressure high - 1 Reports joint ache - 1 Reports
    conjunctivitis - 1 Reports hair loss - 1 Reports voice alteration - 1 Reports angina pectoris aggravated - 1 Reports
    melaena - 1 Reports vomiting blood - 1 Reports muscle contractions involuntary - 1 Reports ear disorder nos - 1 Reports
    bilirubin increased - 1 Reports hepatomegaly - 1 Reports anaphylaxis - 1 Reports psychosis - 1 Reports
    cellulitis - 1 Reports nephropathy toxic - 1 Reports renal tubular disorder - 1 Reports pancreas carcinoma - 1 Reports
    alopecia - 1 Reports psychotic state - 1 Reports dyskinesia - 1 Reports joint stiffness - 1 Reports
    tinnitus - 1 Reports tongue thick - 1 Reports parosmia - 1 Reports nervousness - 1 Reports
    shaking - 1 Reports colon carcinoma - 1 Reports iritis - 1 Reports amnesia - 1 Reports
    disorientation - 1 Reports slurred speech - 1 Reports bruise - 1 Reports delirium - 1 Reports
    urine flow decreased - 1 Reports petechiae - 1 Reports vasculitis - 1 Reports renal failure nos - 1 Reports
    sepsis - 1 Reports hepatic function abnormal - 1 Reports prothrombin decreased - 1 Reports shivers - 1 Reports
    cardiomyopathy - 1 Reports black-out (not amnesia) - 1 Reports gastric carcinoma - 1 Reports prothrombin time prolonged - 1 Reports
    faeces pale - 1 Reports menstrual flow excessive - 1 Reports urine discolouration - 1 Reports fatigue extreme - 1 Reports
    therapeutic response decreased - 1 Reports crohn's disease aggravated - 1 Reports abdominal pain lower - 1 Reports bundle branch block left - 1 Reports
    av block second degree - 1 Reports hypokalaemia - 1 Reports hiccough - 1 Reports burning sensation - 1 Reports
    abscess - 1 Reports pyrexia - 1 Reports abdominal distension - 1 Reports skin flushed - 1 Reports
    anger - 1 Reports crying abnormal - 1 Reports heart block first degree - 1 Reports bone pain - 1 Reports
    diverticulitis - 1 Reports gastrointestinal tract bleed nos - 1 Reports sodium blood decreased - 1 Reports movements involuntary - 1 Reports
    twitching - 1 Reports ldh increased - 1 Reports flatulence - 1 Reports cramp abdominal - 1 Reports
    demyelination - 1 Reports eructation - 1 Reports abdominal pain upper - 1 Reports hiccup - 1 Reports
    influenza-like symptoms - 1 Reports gait unsteady - 1 Reports babinski sign positive - 1 Reports stevens johnson syndrome - 1 Reports
    muscle weakness - 1 Reports mucocutaneous ulceration - 1 Reports cerebrovascular disorder - 1 Reports rash scaly - 1 Reports
    nasal ulcer - 1 Reports pulmonary collapse - 1 Reports sleep difficult - 1 Reports ms aggravated - 1 Reports
    balance difficulty - 1 Reports convulsions grand mal - 1 Reports genital neoplasm malignant male - 1 Reports drug fever - 1 Reports
    obtundation - 1 Reports sinusitis - 1 Reports injection site pain - 1 Reports rectal bleeding - 1 Reports
    aneurysm - 1 Reports semen abnormal - 1 Reports tooth disorder - 1 Reports kidney stone - 1 Reports
    urine abnormal - 1 Reports calcium blood decreased - 1 Reports hypophosphataemia - 1 Reports lipase increased - 1 Reports
    gamma-gt increased - 1 Reports throat irritation - 1 Reports erythema multiforme - 1 Reports extremities hot feeling of - 1 Reports
    temperature changed sensation - 1 Reports drug dependence - 1 Reports heart block second degree - 1 Reports arthritis - 1 Reports
    sleep apnoea - 1 Reports synovitis - 1 Reports joint dysfunction - 1 Reports numbness localized - 1 Reports
    qt prolonged - 1 Reports myoclonus - 1 Reports ophthalmoplegia - 1 Reports paresis - 1 Reports
    mental distress - 1 Reports infection fungal - 1 Reports herpes zoster - 1 Reports neuralgia - 1 Reports
    appetite decreased - 1 Reports gas raising - 1 Reports venous thrombosis - 1 Reports oedema peripheral - 1 Reports
    thrombophlebitis leg superficial - 1 Reports heart attack - 1 Reports pleurisy - 1 Reports accidental overdose - 1 Reports
    anaemia aplastic - 1 Reports suicide attempt - 1 Reports sputum increased - 1 Reports chest pain - 1 Reports
    anaphylactic reaction - 1 Reports faintness - 1 Reports menstrual disorder - 1 Reports acne - 1 Reports
    migraine aggravated - 1 Reports epilepsy - 1 Reports migraine - 1 Reports visual disturbance - 1 Reports
    fracture vertebral - 1 Reports ear ringing - 1 Reports nose dryness - 1 Reports thirst excessive - 1 Reports
    heart disorder - 1 Reports hypertension - 1 Reports serum iron increased - 1 Reports liver fatty - 1 Reports
    spinal cord injury - 1 Reports lacrimation abnormal - 1 Reports hyperaemia eye - 1 Reports eyelid oedema - 1 Reports
    vaginal haemorrhage - 1 Reports hypoaesthesia - 1 Reports feeling hot and cold - 1 Reports scrotal pain - 1 Reports
    dry eyes - 1 Reports skin dry - 1 Reports raynaud's phenomenon - 1 Reports oesophagitis - 1 Reports
    gastritis - 1 Reports tachycardia ventricular - 1 Reports ankle oedema - 1 Reports carcinoma colon - 1 Reports
    bowel obstruction - 1 Reports ecg abnormal - 1 Reports myocardial ischaemia - 1 Reports respiratory failure - 1 Reports
    interstitial lung disease - 1 Reports muscle stiffness - 1 Reports calf pain - 1 Reports osteonecrosis - 1 Reports
    eye pain - 1 Reports brain neoplasm malignant - 1 Reports hemiplegia - 1 Reports dysphasia - 1 Reports
    oedema legs - 1 Reports phlebitis - 1 Reports hyperpotassaemia - 1 Reports renal function abnormal - 1 Reports
    bone disorder - 1 Reports tooth ache - 1 Reports facial palsy - 1 Reports muscle tone flaccid - 1 Reports
    chest tightness of - 1 Reports respiratory disorder - 1 Reports infection - 1 Reports rbc decreased - 1 Reports
    breast oedema - 1 Reports swollen abdomen - 1 Reports difficulty voiding - 1 Reports pain legs - 1 Reports
    pulmonary carcinoma - 1 Reports lactation nonpuerperal - 1 Reports prolactin increased - 1 Reports death - 1 Reports
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