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Bicarbonate has been related to the side effect of Obtundation. If you are taking Bicarbonate and have experienced Obtundation this information may be of use to you.  
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Bicarbonate Drug Insert (if available)
IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.
Bicarbonate Ingredients
  • Bicarbonate
    • Bicarbonate - Obtundation Outcomes
  • Unknown - 1 Reported Cases
    • Bicarbonate - Obtundation Involvements
  • Treatment - 1 Reported Cases
    • Other Reactions Reported While Taking Bicarbonate
    non-accidental overdose - 31 Reports creatinine blood increased - 30 Reports drug level increased - 28 Reports vomiting - 26 Reports
    renal failure acute - 24 Reports creatine kinase increased - 24 Reports tachycardia - 23 Reports rhabdomyolysis - 19 Reports
    hypotension - 18 Reports acidosis metabolic - 17 Reports coma - 17 Reports bradycardia - 16 Reports
    nausea - 16 Reports acidosis - 14 Reports hyperkalaemia - 13 Reports agitation - 13 Reports
    confusion - 11 Reports qrs widened - 11 Reports convulsions - 11 Reports hypokalaemia - 11 Reports
    tinnitus - 11 Reports weakness generalized - 10 Reports cardiac arrest - 10 Reports qt prolonged - 10 Reports
    acidosis lactic - 9 Reports suicide attempt - 9 Reports myoglobinuria - 9 Reports sgot increased - 9 Reports
    unconsciousness - 8 Reports hallucination - 8 Reports sgpt increased - 8 Reports muscle pain - 8 Reports
    tachypnoea - 7 Reports consciousness decreased - 7 Reports potassium serum increased - 7 Reports blood pressure drop arterial - 7 Reports
    salicylism - 7 Reports potassium serum decreased - 7 Reports acidosis respiratory - 6 Reports pupils dilated - 6 Reports
    tremor - 6 Reports respiratory rate increased - 6 Reports diaphoresis - 6 Reports renal tubular necrosis - 5 Reports
    urine discolouration - 5 Reports urea blood level increased - 5 Reports asystolia - 5 Reports alkalosis respiratory - 5 Reports
    disorientation - 5 Reports ldh increased - 5 Reports abdominal pain - 5 Reports muscle weakness - 5 Reports
    hyperventilation - 5 Reports serotonin syndrome - 5 Reports drowsiness - 5 Reports creatine phosphokinase increased - 5 Reports
    respiratory arrest - 4 Reports lethargy - 4 Reports tachycardia ventricular - 4 Reports delirium - 4 Reports
    qrs prolonged - 4 Reports hypoglycaemia - 4 Reports lactate blood increase - 4 Reports dizziness - 4 Reports
    muscle rigidity - 4 Reports tonic/ clonic convulsions - 4 Reports hypothermia - 3 Reports flushing - 3 Reports
    convulsions grand mal - 3 Reports walking difficulty - 3 Reports leukocytosis - 3 Reports anion gap abnormal - 3 Reports
    amylase increased - 3 Reports fibrillation atrial - 3 Reports breath shortness - 3 Reports bronchospasm - 3 Reports
    temperature elevation - 3 Reports ringing in ears - 3 Reports dyspnoea - 3 Reports fatigue - 3 Reports
    shaking - 3 Reports prothrombin time prolonged - 3 Reports speech disorder - 3 Reports proteinuria - 3 Reports
    diarrhoea - 3 Reports fever - 3 Reports bilirubin increased - 3 Reports haematuria - 3 Reports
    alkalosis - 3 Reports malaise - 3 Reports coagulation disorder - 2 Reports death - 2 Reports
    hypoxaemia - 2 Reports sweating increased - 2 Reports bleeding time increased - 2 Reports haemoglobin decreased - 2 Reports
    hypertension - 2 Reports apnoea - 2 Reports pulmonary infiltration - 2 Reports thrombocytopenia - 2 Reports
    hyperreflexia - 2 Reports cpk increased - 2 Reports hepatic enzymes increased - 2 Reports hyperphosphataemia - 2 Reports
    numbness - 2 Reports tingling skin - 2 Reports overdose effect - 2 Reports breathing difficult - 2 Reports
    uric acid blood increased - 2 Reports phosphatase alkaline increased - 2 Reports lipase increased - 2 Reports blisters - 2 Reports
    somnolence - 2 Reports temperature body decrease - 2 Reports pulse rate increased - 2 Reports ph reduced - 2 Reports
    skin cold clammy - 2 Reports bun increased - 2 Reports myalgia - 2 Reports pupils pinpoint - 2 Reports
    slurred speech - 2 Reports arrhythmia - 2 Reports hyperglycaemia - 2 Reports mouth dry - 2 Reports
    combative reaction - 2 Reports blood sugar increased - 2 Reports accidental overdose - 2 Reports hyperthermia malignant - 2 Reports
    anxiety - 2 Reports renal acidosis tubular - 2 Reports blood urea nitrogen increased - 2 Reports twitching - 2 Reports
    myoclonus - 2 Reports pallor - 2 Reports arrhythmia ventricular - 2 Reports medication error - 2 Reports
    back pain - 2 Reports memory impairment - 2 Reports respiratory rate decreased - 2 Reports renal failure nos - 2 Reports
    alkaline phosphatase serum incr - 2 Reports gamma-gt increased - 2 Reports deafness - 2 Reports pneumonia - 2 Reports
    nephritis interstitial - 1 Reports atrial flutter - 1 Reports alkalosis metabolic - 1 Reports pupils fixed - 1 Reports
    irritability - 1 Reports st depressed - 1 Reports post-operative haemorrhage - 1 Reports wound drainage increased - 1 Reports
    cyanosis - 1 Reports bradypnoea - 1 Reports anaphylaxis - 1 Reports pulmonary haemorrhage - 1 Reports
    respiratory distress - 1 Reports haemoptysis - 1 Reports purpura - 1 Reports blood pressure increased - 1 Reports
    hypovolaemia - 1 Reports hypocalcaemia - 1 Reports neuropathy peripheral - 1 Reports herpes zoster - 1 Reports
    myocarditis - 1 Reports anaemia - 1 Reports candidiasis - 1 Reports brachial plexus lesion - 1 Reports
    muscle atrophy - 1 Reports calcium blood decreased - 1 Reports weakness voluntary muscle - 1 Reports pain legs - 1 Reports
    myopathy - 1 Reports anorexia - 1 Reports muscle wasting - 1 Reports hyporeflexia - 1 Reports
    dysaesthesia - 1 Reports pain groin - 1 Reports pancreatitis - 1 Reports renal failure aggravated - 1 Reports
    vomiting blood - 1 Reports icterus - 1 Reports responses voluntary reduced - 1 Reports multiple organ failure - 1 Reports
    urine volume deficient - 1 Reports oedema cerebral - 1 Reports oesophageal ulceration - 1 Reports respiratory failure - 1 Reports
    shock - 1 Reports pr interval prolonged - 1 Reports skin dry - 1 Reports skin flushed - 1 Reports
    convulsions aggravated - 1 Reports burn - 1 Reports abdominal discomfort - 1 Reports hot flushes - 1 Reports
    sleepiness - 1 Reports therapeutic response increased - 1 Reports qrs increase in time - 1 Reports paraesthesia - 1 Reports
    status epilepticus - 1 Reports diabetic ketoacidosis - 1 Reports hyponatraemia - 1 Reports shivers - 1 Reports
    mydriasis - 1 Reports obtundation - 1 Reports infection - 1 Reports hearing decreased - 1 Reports
    mentation impaired - 1 Reports bundle branch block right - 1 Reports arterial blood pressure decreased - 1 Reports altered state of consciousness - 1 Reports
    impulsive behaviour - 1 Reports herpes lesion intra-oral - 1 Reports hearing impaired - 1 Reports neutrophilia - 1 Reports
    sudden death - 1 Reports pulmonary oedema - 1 Reports encephalopathy - 1 Reports pulmonary congestion - 1 Reports
    hyperchloraemia - 1 Reports drug abuse - 1 Reports pre-syncope - 1 Reports heart block complete - 1 Reports
    hepatic failure - 1 Reports myocardial infarction - 1 Reports rash - 1 Reports ketosis - 1 Reports
    blood in urine - 1 Reports ketoacidosis - 1 Reports asterixis - 1 Reports gait unsteady - 1 Reports
    prothrombin time shortened - 1 Reports epigastric pain not food-related - 1 Reports thoracic pain - 1 Reports oedema of extremities - 1 Reports
    coughing - 1 Reports influenza-like symptoms - 1 Reports prothrombin decreased - 1 Reports bruise - 1 Reports
    circulatory instability - 1 Reports haemolysis - 1 Reports ecg abnormal - 1 Reports jaundice - 1 Reports
    myoclonic jerks - 1 Reports ataxia - 1 Reports sedation - 1 Reports urinary incontinence - 1 Reports
    pain - 1 Reports anuria - 1 Reports alp increased - 1 Reports renal failure chronic - 1 Reports
    feeling of warmth - 1 Reports hallucination visual - 1 Reports aspiration - 1 Reports respiratory disorder - 1 Reports
    hyperuricaemia - 1 Reports sinus tachycardia - 1 Reports neuroleptic malignant syndrome - 1 Reports pupils constricted - 1 Reports
    pupillary reflex impaired - 1 Reports drug withdrawal syndrome - 1 Reports blood pressure high - 1 Reports hypoxia - 1 Reports
    hyperpnoea - 1 Reports aspiration pneumonitis - 1 Reports respiratory depression - 1 Reports rash erythematous - 1 Reports
    vasoconstriction - 1 Reports anaphylactic reaction - 1 Reports leg pain - 1 Reports fibrillation atrial aggravated - 1 Reports
    tiredness - 1 Reports immunoglobulins increased - 1 Reports bundle branch block - 1 Reports hallucination auditory - 1 Reports
    miosis - 1 Reports panic reaction - 1 Reports syncope - 1 Reports wooziness - 1 Reports
    cardiac failure right - 1 Reports pulse abnormal - 1 Reports hearing reduced - 1 Reports depression - 1 Reports
    blood urea increased - 1 Reports dehydration - 1 Reports erythema - 1 Reports hair thinning - 1 Reports
    hives - 1 Reports haematemesis - 1 Reports shock septic - 1 Reports urticaria - 1 Reports
    anaphylactoid reaction - 1 Reports feeling unwell - 1 Reports paralysis - 1 Reports pulse rate decrease marked - 1 Reports
    confusional state - 1 Reports urinary casts - 1 Reports bicarbonate reserve decreased - 1 Reports hypocapnia - 1 Reports
    neurologic disorder nos - 1 Reports stupor - 1 Reports diabetes insipidus - 1 Reports hypercalcaemia - 1 Reports
    hypopotassaemia - 1 Reports hypernatraemia - 1 Reports hypomagnesaemia - 1 Reports
    Bicarbonate Uses

    Sodium bicarbonate - Wikipedia, the free encyclopedia

    5.3 Medical uses. 5.4 As a cleaning agent. 5.5 Miscellaneous. 6 See also ... innocuous in most situations there is no harm in using excess sodium bicarbonate. ...en.wikipedia.org/wiki/Sodium_bicarbonate - 55k - Cached

    Ammonium bicarbonate - Wikipedia, the free encyclopedia

    ... room temperature ammonium bicarbonate is a white, crystalline ... [edit] Uses. Ammonium bicarbonate is used in the food industry as a raising agent (e.g., for ...en.wikipedia.org/wiki/Ammonium_bicarbonate - Cached

    SODIUM BICARBONATE - ORAL side effects, medical uses, and drug interactions.

    Read more about the prescription drug SODIUM BICARBONATE - ORAL. ... Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions ...www.medicinenet.com/sodium_bicarbonate-oral/article.htm - Cached

    Sodium Bicarbonate (40:08) - 382001

    ... of or against the use of sodium bicarbonate in adult or pediatric ... (See Uses.) The manufacturers recommend that severe bicarbonate-induced alkalosis ...www.ashp.org/mngrphs/ahfs/a382001.htm - 60k - Cached

    Bicarbonate of Soda-helpful household hints

    Add two full tablespoons Bicarbonate of Soda to the usual amount of detergent you use. ... Use as a deodorant. Dust Bicarbonate of Soda under arms. ...www.virtuowl.com/home/bicarb-uses.htm - Cached
    General Information on Bicarbonate related to Obtundation

    Diabetic Ketoacidosis - May 1, 2005 - American Family Physician
    Alteration in sensoria or mental obtundation. Alert. Alert/drowsy. Stupor/coma ... of patients with a pH level of 6.9 or higher have found no evidence that bicarbonate ...

    Management of Diabetic Ketoacidosis - August 1999 - American Academy ...
    If bicarbonate is used, it should be given as a nearly isotonic solution, which can be ... or oliguria refractory to initial rehydration and for patients with mental obtundation ...

    010198 Management of Life-Threatening Acid?Base
    Whereas patients with very low plasma bicarbonate concentrations can have a bicarbonate ... protein degradation Cerebral Inhibition of metabolism and cell-volume regulation Obtundation ...

    Endotext.com - Diabetes, Insulin signaling and action: glucose, lipids ...
    Table 2 shows that only glucose, bicarbonate, BUN and osmolality, but not pH , were ... 150-200 mg/dl in DKA and 250-300 mg/dl for HHS until DKA is resolved or mental obtundation ...

    NEJM -- Risk Factors for Cerebral Edema in Children with Diabetic ...
    ... a venous pH <7.25 or a serum bicarbonate concentration <15 mmol per liter, and the presence of ketones [acetoacetate] in the urine); alteration in mental status (obtundation or ...
    Bicarbonate Settlements

    Lithium - Adverse drug reactions causing Cyanosis - case studies for ...
    bicarbonate reserve decreased - 1 Reports: calcium increased ... obtundation - 1 Reports: thinking irrational - 1 Reports ... Lithium Settlements: Potential Risks and Prevention, Part 3

    Epival - Adverse drug reactions causing Fear - case studies for Fear ...
    obtundation - 1 Reports: infection - 1 Reports: ageusia - 1 ... bicarbonate reserve decreased - 1 Reports: healing impaired ... Epival Settlements: MyTherapy Discussion Forums - 4 wheel ...

    Fluoxetine - Adverse drug reactions causing Impotence - case studies ...
    obtundation - 1 Reports: anuria - 1 Reports: fluid retention in ... bicarbonate reserve decreased - 1 Reports: hot flushes - 1 ... Fluoxetine Settlements: Fluoxetine Interactions: Impotence ...

    Gravol - Adverse drug reactions causing Hallucination - case studies ...
    ... as an reaction to Gravol Remedies! Recalls! Settlements (get ... obtundation - 2 Reports: red eye - 2 Reports: hypotension ... bicarbonate reserve decreased - 2 Reports: appetite impaired ...

    The Ten Foot Stop: April 2006
    The terms of the settlement remain confidential. The SSS Network of Recompression ... Renal disease can cause changes in the sensorium due to obtundation from elevations in ...
    Bicarbonate Interactions

    8.2 Ketoacidosis
    For each anion produced there is a loss of one bicarbonate. ... Respiratory acidosis due to pneumonia or mental obtundation. Respiratory alkalosis with sepsis ...

    DiabetoValens.com - The Diabetes Guide
    ... alteration in mental status (obtundation or disorientation); and either ... In addition, bicarbonate therapy causes central nervous system hypoxia in ...

    Management of Hyperglycemic Crises in Patients With Diabetes: Treatment
    ... greater level of mental obtundation in HHS, we have ... Bicarbonate ... Goldberg D, Walesky M: Hormonal interactions in the regulation of blood glucose. ...

    Quinine
    ... intoxication may cause ataxia, obtundation, convulsions, coma, and respiratory arrest. ... Treat cardiotoxicity with sodium bicarbonate. ... Drug Interactions: ...

    Management of Hyperglycemic Crises in Patients With Diabetes ...
    ... Goldberg D, Walesky M: Hormonal interactions in the regulation of blood ... Lever E, Jaspan JB: Sodium bicarbonate therapy in severe diabetic ketoacidosis. ...
    Bicarbonate Recalls

    sodium bicarbonate; Greenville North Carolina NC
    sodium bicarbonate - University Health Systems of Greenville North Carolina serves tarboro, ahoskie, ... Future of Medicine Health Observances Product Recalls ...

    Bicarbonate Test Overview; Greenville North Carolina NC
    Bicarbonate Test Overview - University Health Systems of Greenville North Carolina serves tarboro, ... Future of Medicine Health Observances Product Recalls ...

    SEPTEMBER 2003
    PRODUCT INFANT 4.2% Sodium Bicarbonate Injection, USP, 5 mEq (0.5 ... carton labeled as Infant 4.2% Sodium Bicarbonate Injection, USP. ... initiated recall is ...

    AUGUST 2000
    Sodium Bicarbonate Oral Powder, USP, 4 oz bottle, Humco Trademark. CODE Sulfur Sublimed Sodium Bicarbonate. Powder USP Oral Powder USP. Lot No 237059 272629 ...

    ENFORCEMENT REPORT FOR APRIL 10, 2002
    Recall # D-219-2. Sodium Bicarbonate Oral Powder, USP, 4 oz bottle, Humco Trademark. ... OK, TN, and WI. RECALLS AND FIELD CORRECTIONS: DRUGS -- CLASS ...
    Bicarbonate Side Effects

    Numark Laboratories: Innovative treatments for unique medical ...
    Other common side effects include dizziness, incoordination ... Larger doses can cause obtundation, miosis, severe ... Acetazolamide inhibits sodium bicarbonate reabsorption in ...

    Primary Viva Questions -Pharmacology
    Obtundation of the pressor response to intubation Precautions with ... Side effects of sodium bicarbonate Mechanism of action of mannitol Colloids; mannitol

    Ammonul (Sodium Phenylacetate and Sodium Benzoate Injection) Drug ...
    Learn about the prescription medication Ammonul (Sodium Phenylacetate and Sodium Benzoate Injection), drug uses, dosage, side effects, drug interactions, warnings, and patient ...

    hypercalcemia
    ... poor concentration, depression => obtundation ... 40%) or complexed to anions eg. bicarbonate ... is seen within 1 - 2 days but the nadir effect is delayed 3 - 7 days - side ...

    Symbyax (Olanzapine and fluoxetine) Drug Information: Uses, Side ...
    ... medication Symbyax (Olanzapine and fluoxetine), drug uses, dosage, side effects, drug ... 8%); elevated uric acid (2.9% vs 0.5%); low albumin (2.7% vs 0.3%); low bicarbonate ...
    Obtundation - Bicarbonate Remedies

    The Journal of Urgent Care Medicine: June 2008 Issue
    Mental obtundation and coma are common findings, and focal ... and phosphate levels are typically normal, while bicarbonate ... 9% saline is given over the first few hours to remedy ...

    Part 8: Advanced Challenges in Resuscitation : Section 3: Special ...
    Findings of obtundation; Profuse diaphoresis; Poor ("floppy") muscle tone (clinical signs of ... The ensuing drop in pH can be controlled with bicarbonate if needed. To set the ventilator ...

    Ammonul (Sodium Phenylacetate and Sodium Benzoate Injection) Drug ...
    AMMONULŪ (sodium phenylacetate and sodium benzoate) Injection 10% /10% is a ... Home Remedies for Warts; Teen Drug Slang You Should Know; How to Choose the Right OTC Medication

    DB?s Medical Rants
    The Family Doctor: A Remedy for Health-Care Costs? ? of ... Delta gap supports bicarbonate of 33 (add 9 to 24 ? the 9 ... Now presents with increasing obtundation, increased urination ...

    Noninvasive Ventilation -- MEHTA and HILL 163 (2): 540 -- American ...
    Am. J. Respir. Crit. Care Med., Volume 163, Number 2, February 2001, 540-577 Noninvasive Ventilation SANGEETA MEHTA and NICHOLAS S. HILL. Divisions of Pulmonary and Critical Care ...
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