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Amiodarone has been related to the side effect of Obtundation. If you are taking Amiodarone and have experienced Obtundation this information may be of use to you.  
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Amiodarone Drug Insert (if available)
IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.
Amiodarone Ingredients
  • Amiodarona
  • Amiodarone
  • Amiodaronum
  • Amjodaronum
    • Amiodarone - Obtundation Outcomes
  • Unknown - 1 Reported Cases
    • Amiodarone - Obtundation Involvements
  • Concomitant - 1 Reported Cases
    • Other Reactions Reported While Taking Amiodarone
    breath shortness - 57 Reports creatinine blood increased - 48 Reports drug level increased - 37 Reports nausea - 36 Reports
    bradycardia - 36 Reports tachycardia ventricular - 35 Reports fibrillation atrial - 34 Reports hypotension - 30 Reports
    chest pain - 26 Reports cardiac arrest - 26 Reports weakness generalized - 25 Reports dyspnoea - 24 Reports
    qt prolonged - 24 Reports dizziness - 23 Reports sgot increased - 23 Reports diarrhoea - 22 Reports
    coughing - 22 Reports myocardial infarction - 20 Reports torsade de pointes - 19 Reports thrombocytopenia - 19 Reports
    sgpt increased - 19 Reports vomiting - 18 Reports itching - 18 Reports fever - 18 Reports
    pneumonia - 18 Reports palpitation - 17 Reports efficacy, lack of - 17 Reports syncope - 17 Reports
    haemoglobin decreased - 15 Reports prothrombin time prolonged - 15 Reports congestive heart failure - 15 Reports fatigue - 14 Reports
    fibrillation ventricular - 14 Reports confusion - 14 Reports pulmonary fibrosis - 14 Reports renal failure acute - 13 Reports
    condition aggravated - 13 Reports respiratory failure - 13 Reports tachycardia - 13 Reports dehydration - 12 Reports
    liver function tests abnormal nos - 12 Reports hepatic enzymes increased - 12 Reports anorexia - 11 Reports arrhythmia - 11 Reports
    pulmonary infiltration - 11 Reports rash - 11 Reports bun increased - 11 Reports fall - 11 Reports
    erythema - 10 Reports malaise - 10 Reports abdominal pain - 10 Reports tremor - 10 Reports
    hyperkalaemia - 10 Reports pruritus - 10 Reports potassium serum increased - 10 Reports hypoglycaemia - 10 Reports
    diaphoresis - 10 Reports unconsciousness - 9 Reports rash erythematous - 9 Reports weight decrease - 9 Reports
    drowsiness - 9 Reports pulmonary oedema - 9 Reports bilirubin increased - 9 Reports arrhythmia ventricular - 9 Reports
    creatine kinase increased - 9 Reports interstitial lung disease - 8 Reports muscle weakness - 8 Reports hyperthyroidism - 8 Reports
    neutropenia - 8 Reports renal failure nos - 8 Reports anaemia - 8 Reports alkaline phosphatase serum incr - 8 Reports
    breathing difficult - 7 Reports hypokalaemia - 7 Reports urea blood level increased - 7 Reports hypoxaemia - 7 Reports
    sepsis - 7 Reports gamma-gt increased - 7 Reports bleeding time increased - 7 Reports hypothyroidism - 7 Reports
    headache - 7 Reports hypoxia - 7 Reports cardiac failure - 7 Reports hypertension - 6 Reports
    respiratory disorder - 6 Reports oedema pulmonary - 6 Reports pain - 6 Reports stroke - 6 Reports
    ldh increased - 6 Reports light-headed feeling - 6 Reports sweating increased - 6 Reports chills - 6 Reports
    angioedema - 6 Reports pleural effusion - 6 Reports blood pressure increased - 6 Reports hyperglycaemia - 6 Reports
    cardiomyopathy - 5 Reports sinus bradycardia - 5 Reports heart attack - 5 Reports coagulation disorder - 5 Reports
    feeling unwell - 5 Reports leukocytosis - 5 Reports oedema legs - 5 Reports tachypnoea - 5 Reports
    jaundice - 5 Reports renal function abnormal - 5 Reports constipation - 5 Reports acidosis metabolic - 5 Reports
    haemorrhage retroperitoneal - 5 Reports congestive cardiac failure aggr - 5 Reports appetite decreased - 5 Reports prothrombin time shortened - 5 Reports
    oedema - 5 Reports hepatitis - 5 Reports walking difficulty - 5 Reports ecg abnormal - 4 Reports
    rash maculo-papular - 4 Reports back pain - 4 Reports convulsions - 4 Reports pulse rate increased - 4 Reports
    anuria - 4 Reports multiple organ failure - 4 Reports tsh increased - 4 Reports tsh decreased - 4 Reports
    burning sensation - 4 Reports angina pectoris - 4 Reports renal failure aggravated - 4 Reports acidosis lactic - 4 Reports
    coronary artery disorder - 4 Reports muscle pain - 4 Reports adult respiratory distress syndr - 4 Reports tiredness - 4 Reports
    consciousness decreased - 4 Reports flushing - 4 Reports allergic reaction - 4 Reports delirium - 4 Reports
    hepatic failure - 4 Reports hepatic cirrhosis - 4 Reports therapeutic response decreased - 4 Reports blood pressure drop arterial - 4 Reports
    pneumonitis - 4 Reports blood sugar increased - 4 Reports cramp abdominal - 4 Reports bundle branch block left - 4 Reports
    cerebral haemorrhage - 4 Reports haematoma - 4 Reports resp gas exchange disorder nos - 4 Reports hallucination - 3 Reports
    paraesthesia - 3 Reports haemoptysis - 3 Reports blisters - 3 Reports diarrhoea, clostridium difficile - 3 Reports
    acidosis - 3 Reports tachycardia supraventricular - 3 Reports st depressed - 3 Reports hypocalcaemia - 3 Reports
    hypomagnesaemia - 3 Reports asystolia - 3 Reports slurred speech - 3 Reports arrhythmia atrial - 3 Reports
    alveolitis - 3 Reports hepatic function abnormal - 3 Reports muscle cramp - 3 Reports cardiac arrhythmia nos - 3 Reports
    insomnia - 3 Reports heart failure - 3 Reports heart block - 3 Reports abdominal distension - 3 Reports
    haematuria - 3 Reports face oedema - 3 Reports hyponatraemia - 3 Reports vision blurred - 3 Reports
    urticaria - 3 Reports pulmonary congestion - 3 Reports collapse transient - 3 Reports strength loss of - 3 Reports
    hives - 3 Reports oliguria - 3 Reports twitching - 3 Reports bruise - 3 Reports
    temperature elevation - 3 Reports tingling skin - 3 Reports phosphatase alkaline increased - 3 Reports prothrombin decreased - 3 Reports
    vision abnormal - 3 Reports haemorrhage nos - 3 Reports oedema peripheral - 3 Reports weight increase - 3 Reports
    rbc decreased - 3 Reports tongue swelling non-specific - 3 Reports cardiac failure aggravated - 3 Reports faintness - 3 Reports
    thyrotoxicosis - 3 Reports gi haemorrhage - 3 Reports stool black - 3 Reports heart disorder - 3 Reports
    sputum increased - 3 Reports extrasystole ventricular - 3 Reports osteonecrosis - 3 Reports ascites - 3 Reports
    leg pain - 3 Reports pleurisy - 2 Reports epigastric pain not food-related - 2 Reports therapeutic response increased - 2 Reports
    nephritis interstitial - 2 Reports fatigue extreme - 2 Reports pulse irregularity nos - 2 Reports tinnitus - 2 Reports
    qrs prolonged - 2 Reports mottled skin - 2 Reports pulmonary haemorrhage - 2 Reports hepatotoxic effect - 2 Reports
    encephalopathy - 2 Reports leucopenia - 2 Reports gamma-glutamyltransferase incr. - 2 Reports skin dry - 2 Reports
    t4 increased - 2 Reports thyroiditis - 2 Reports suicide attempt - 2 Reports papular rash - 2 Reports
    neurotoxicity - 2 Reports spasms - 2 Reports cellulitis - 2 Reports cholecystitis - 2 Reports
    ototoxicity - 2 Reports rectal bleeding - 2 Reports angina pectoris aggravated - 2 Reports appetite lost - 2 Reports
    chest tightness of - 2 Reports pain neck/shoulder - 2 Reports vertigo - 2 Reports lactate blood increase - 2 Reports
    depression - 2 Reports mouth dry - 2 Reports st elevated - 2 Reports dyspepsia - 2 Reports
    respiratory insufficiency - 2 Reports shock cardiogenic - 2 Reports cardiomegaly - 2 Reports myocardial ischaemia - 2 Reports
    oedema of extremities - 2 Reports haemorrhage intracranial - 2 Reports respiratory distress - 2 Reports rash petechial - 2 Reports
    pancytopenia - 2 Reports gastrointestinal tract bleed nos - 2 Reports melaena - 2 Reports disorientation - 2 Reports
    c-reactive protein positive - 2 Reports retinal haemorrhage - 2 Reports chest pressure sensation of - 2 Reports thoracic pain - 2 Reports
    respiratory rate increased - 2 Reports ldh increased serum - 2 Reports pericardial effusion - 2 Reports chest x-ray abnormal - 2 Reports
    injection site reaction - 2 Reports convulsions grand mal - 2 Reports hepatic steatosis - 2 Reports somnolence - 2 Reports
    taste perversion - 2 Reports shaking - 2 Reports apnoea - 2 Reports embolism - blood clot - 2 Reports
    heart block first degree - 2 Reports ataxia - 2 Reports pre-syncope - 2 Reports lips swelling non-specific - 2 Reports
    pulmonary carcinoma - 2 Reports joint pain - 2 Reports bullous eruption - 2 Reports urinary tract infection - 2 Reports
    prostatic disorder - 2 Reports heart murmur - 2 Reports renal failure chronic - 2 Reports pulse rate decrease marked - 2 Reports
    aplasia, pure red cell - 2 Reports anaphylactoid reaction - 2 Reports respiratory depression - 2 Reports anaemia aplastic - 2 Reports
    antibodies drug specific - 2 Reports av block - 2 Reports medication error - 2 Reports death - 2 Reports
    non-accidental overdose - 2 Reports coronary artery occlusion - 2 Reports bronchitis - 2 Reports esr increased - 2 Reports
    hypotension orthostatic - 2 Reports lethargy - 2 Reports dysphagia - 2 Reports tooth disorder - 2 Reports
    thrombosis venous deep - 2 Reports arthralgia - 2 Reports skin cold clammy - 2 Reports agitation - 2 Reports
    neutrophilia - 2 Reports sinus tachycardia - 2 Reports atrial flutter - 2 Reports aortic stenosis - 2 Reports
    rash purpuric - 2 Reports neuropathy peripheral - 2 Reports fatigueability - 2 Reports hemothorax - 2 Reports
    alp increased - 2 Reports ecchymosis - 2 Reports passed out - 2 Reports gastro-intestinal disorder nos - 2 Reports
    le rash - 1 Reports nightmares - 1 Reports sudden death - 1 Reports hiccough - 1 Reports
    sensory disturbance - 1 Reports platelet production decreased - 1 Reports colitis pseudomembranous - 1 Reports bone fracture spontaneous - 1 Reports
    inflicted injury - 1 Reports skeletal pain - 1 Reports pneumonitis allergic - 1 Reports thrombosis arterial arm - 1 Reports
    ischaemia peripheral - 1 Reports necrosis ischaemic - 1 Reports gangrene - 1 Reports vasospasm - 1 Reports
    thrombophlebitis deep - 1 Reports status epilepticus - 1 Reports urinary incontinence - 1 Reports muscle stiffness - 1 Reports
    t wave inversion - 1 Reports feeling cold - 1 Reports hyperchloraemia - 1 Reports myositis - 1 Reports
    vasculitis - 1 Reports stupor - 1 Reports petechiae - 1 Reports embolism limb - 1 Reports
    hypoprothrombinaemia - 1 Reports responses voluntary reduced - 1 Reports panic reaction - 1 Reports cramps legs - 1 Reports
    adult respiratory stress syndrome - 1 Reports muscle ache - 1 Reports hepatitis toxic - 1 Reports anxiety attack - 1 Reports
    numbness localized - 1 Reports sensation of cold - 1 Reports hyperventilation - 1 Reports vein disorder - 1 Reports
    flank pain - 1 Reports blindness - 1 Reports creatinine clearance decreased - 1 Reports coronary spasm - 1 Reports
    exophthalmos - 1 Reports hypophosphataemia - 1 Reports hypernatraemia - 1 Reports infection localised - 1 Reports
    bone marrow depression - 1 Reports mucositis nos - 1 Reports fibrillation cardiac nos - 1 Reports respiratory arrest - 1 Reports
    drug level decreased - 1 Reports cyanosis peripheral - 1 Reports cachexia - 1 Reports kidney dysfunction - 1 Reports
    swallowing impaired - 1 Reports tachycardia nodal - 1 Reports accidental overdose - 1 Reports chest burning pain of - 1 Reports
    throat tightness - 1 Reports thrombocythaemia - 1 Reports creatine phosphokinase increased - 1 Reports gall bladder disorder - 1 Reports
    intestinal dilatation - 1 Reports abdominal distress - 1 Reports herpes simplex - 1 Reports atrial flutter/ fibrillation - 1 Reports
    hypertension aggravated - 1 Reports arrhythmia supraventricular - 1 Reports thyroid stim. hormone decreased - 1 Reports vascular disorder - 1 Reports
    optic neuritis - 1 Reports hyperbilirubinaemia - 1 Reports hyperaemia eye - 1 Reports anaphylactic reaction - 1 Reports
    coma hepatic - 1 Reports urine discolouration - 1 Reports scleral discolouration - 1 Reports bilirubinaemia - 1 Reports
    amylase increased - 1 Reports neuropathy - 1 Reports influenza-like symptoms - 1 Reports cardiac tamponade - 1 Reports
    throat irritation - 1 Reports injection site inflammation - 1 Reports leukaemoid reaction - 1 Reports pain right upper quadrant - 1 Reports
    muscle contractions involuntary - 1 Reports flatulence - 1 Reports indigestion - 1 Reports visual field defect - 1 Reports
    jaw pain - 1 Reports phlebitis - 1 Reports injection site pain - 1 Reports marrow hypoplasia - 1 Reports
    serum iron increased - 1 Reports scotoma - 1 Reports hypersensitivity - 1 Reports water retention in tissues - 1 Reports
    weariness - 1 Reports electric shock sensation - 1 Reports anion gap abnormal - 1 Reports drug maladministration - 1 Reports
    bladder carcinoma - 1 Reports rhabdomyolysis - 1 Reports gynaecomastia - 1 Reports urinary retention - 1 Reports
    nocturia - 1 Reports skin ulceration - 1 Reports swelling non-inflammatory - 1 Reports hypertriglyceridaemia - 1 Reports
    retrosternal pain - 1 Reports macular rash - 1 Reports ectopic beats - 1 Reports tachycardia atrial - 1 Reports
    vision double - 1 Reports hot flushes - 1 Reports gastric ulcer perforated - 1 Reports lymphopenia - 1 Reports
    hearing decreased - 1 Reports pancreatitis - 1 Reports urinary frequency - 1 Reports skin disorder - 1 Reports
    haemolysis - 1 Reports obtundation - 1 Reports oesophageal varices - 1 Reports corneal opacity - 1 Reports
    dissem. intravasc. coagulation - 1 Reports platelets abnormal - 1 Reports pupils dilated - 1 Reports coronary insufficiency - 1 Reports
    mitral insufficiency - 1 Reports atrioventricular block - 1 Reports muscle fasciculation - 1 Reports thirst - 1 Reports
    siadh - 1 Reports cardiac failure left - 1 Reports thrombosis pulmonary - 1 Reports mobility decreased - 1 Reports
    incoordination - 1 Reports sinus arrest - 1 Reports blood urea nitrogen increased - 1 Reports uric acid blood increased - 1 Reports
    renal artery stenosis - 1 Reports heat intolerance - 1 Reports anaemia normochromic - 1 Reports anaemia normocytic - 1 Reports
    fibrillation cardiac - 1 Reports blood sugar decreased - 1 Reports anaphylactic shock - 1 Reports asthenia - 1 Reports
    fibrillation atrial aggravated - 1 Reports larynx oedema - 1 Reports embolism pulmonary - 1 Reports stridor - 1 Reports
    androgen excess effect - 1 Reports colitis - 1 Reports mental deficiency - 1 Reports chronic obstruct airways disease - 1 Reports
    chest discomfort - 1 Reports epistaxis - 1 Reports mouth haemorrhage - 1 Reports myocarditis - 1 Reports
    renal tubular necrosis - 1 Reports av block first degree - 1 Reports bundle branch block right - 1 Reports lung infiltration - 1 Reports
    osteomyelitis - 1 Reports breast cancer - 1 Reports application site reaction - 1 Reports rash scaly - 1 Reports
    myoclonus - 1 Reports pallor - 1 Reports coma hyperglycaemic - 1 Reports hyperosmolar state - 1 Reports
    mouth irritation - 1 Reports hepatic disease - 1 Reports paralysis - 1 Reports pain legs - 1 Reports
    hepatomegaly - 1 Reports splenomegaly - 1 Reports movements reduced - 1 Reports nystagmus congenital - 1 Reports
    hypothyroidism congenital - 1 Reports qrs widened - 1 Reports oedema periorbital - 1 Reports reflexes abnormal - 1 Reports
    hemiplegia - 1 Reports speech disorder - 1 Reports infection fungal - 1 Reports nail disorder - 1 Reports
    calf pain - 1 Reports nasal congestion - 1 Reports sneezing excessive - 1 Reports temperature changed sensation - 1 Reports
    infection - 1 Reports sleep disorder - 1 Reports memory loss - 1 Reports black-out (not amnesia) - 1 Reports
    sodium blood decreased - 1 Reports diabetes mellitus - 1 Reports urine production scanty - 1 Reports stools watery - 1 Reports
    small intestine obstruction - 1 Reports retrobulbar neuritis - 1 Reports eye pain - 1 Reports dry eyes - 1 Reports
    visual evoked potentials abnorm. - 1 Reports demyelination - 1 Reports numbness - 1 Reports liver tender - 1 Reports
    pneumonia interstitial - 1 Reports collagenosis - 1 Reports hypoaesthesia - 1 Reports neuromuscular block - 1 Reports
    amnesia - 1 Reports angioneurotic oedema - 1 Reports prothrombin increased - 1 Reports hearing reduced - 1 Reports
    t4 decreased - 1 Reports ocular hyperaemia - 1 Reports sedation - 1 Reports achilles tendon injury - 1 Reports
    sputum bloody - 1 Reports collapse circulatory - 1 Reports lung fibrosis interstitial - 1 Reports gastroesophageal reflux - 1 Reports
    spotting between menses - 1 Reports clotting time increased - 1 Reports stomach upset - 1 Reports confusional state - 1 Reports
    appetite absent - 1 Reports suicide - 1 Reports visual impairment - 1 Reports coma - 1 Reports
    conjunctival haemorrhage - 1 Reports ecg/ekg changes non-specific - 1 Reports cns depression nos - 1 Reports muscle haemorrhage - 1 Reports
    cognitive function abnormal - 1 Reports abdominal pain upper - 1 Reports vomiting blood - 1 Reports heart valve disorders - 1 Reports
    anxiety - 1 Reports transplant rejection - 1 Reports ear disorder nos - 1 Reports bundle branch block - 1 Reports
    azotemia - 1 Reports myopathy - 1 Reports hepatocellular damage - 1 Reports cyanosis - 1 Reports
    respiratory dysfunction nos - 1 Reports thrombosis venous superficial - 1 Reports mental distress - 1 Reports fluid overload - 1 Reports
    therapeutic effect unexpected - 1 Reports hypertension portal - 1 Reports thrombosis - 1 Reports hyperammonaemia - 1 Reports
    antinuclear factor test positive - 1 Reports carcinoma squamous - 1 Reports fracture femur - 1 Reports bone disorder - 1 Reports
    hip dislocation - 1 Reports metastases nos - 1 Reports bone pain - 1 Reports taste peculiar - 1 Reports
    cerebral vascular disturbance - 1 Reports apathy - 1 Reports breathing arrested - 1 Reports fracture pathological - 1 Reports
    ankle oedema - 1 Reports joint swelling non-inflammatory - 1 Reports muscle disorder - 1 Reports infection staphylococcal - 1 Reports
    hypercapnia - 1 Reports respiratory lesion - 1 Reports oedema mouth - 1 Reports blood pressure fluctuation - 1 Reports
    inflammation localized - 1 Reports eye abnormality - 1 Reports hoarseness - 1 Reports cataract - 1 Reports
    hallucination auditory - 1 Reports atrial fibrillation paroxysmal - 1 Reports arthritis - 1 Reports haemosiderosis - 1 Reports
    flash vision - 1 Reports photophobia - 1 Reports
    Amiodarone Uses

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    Amiodarone Interactions

    Toxicity, Antidysrhythmic: Overview - eMedicine

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    ... are characterized by either obtundation (dulled consciousness) or the ... Amiodarone hepatitis can be untreatable since the long half life of the drug (up ...en.wikipedia.org/wiki/Hepatitis_virus

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    Emergency Medicine

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    Device Recalls
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    Recalls, Market Withdrawals and Safety Alerts Archive: 2004
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